Ahmed Ismaeel

This study shows that transplanting L6 myotube mitochondria reduces hypertrophy and alters proteomic pathways in phenylephrine-treated H9C2 cardiomyocytes.

The paper identifies age-related differences in the transcriptional states of MuSC-derived myonuclei in response to mechanical overload.

The paper shows that transient MYC activation in skeletal muscle mimics exercise-induced adaptations, leading to hypertrophy, metabolic changes, and fiber type shifts.

This study examines age-related differences in myonuclear multi-omic responses to muscle hypertrophy in mice, identifying transcriptional, epigenetic, and regulatory mechanisms underlying age-dependent muscle plasticity.

This study shows miR-1 regulates metabolic flexibility in skeletal muscle by controlling pyruvate metabolism, with loss of miR-1 causing metabolic inflexibility and reduced endurance.

The paper shows that microbial-derived exerkines from exercise-trained mice prevent skeletal muscle atrophy in a hindlimb-immobilization model.