Polybacterial Intracellular Macromolecules Shape Single-Cell Epikine Profiles in Upper Airway Mucosa
Quinn T. Easter, Zabdiel Alvarado‐Martinez, Meik Kunz, Bruno Fernandes Matuck, Brittany Rupp, Theresa M. Weaver, Zhi Feng Ren, Aleksandra Tata, Juan Caballero-Pérez, Nick Oscarson, Akira Hasuike, Ameer Ghodke, Adam J. Kimple, Purushothama Rao Tata, Scott H. Randell, , Kevin M. Byrd
This study reveals how persistent intracellular bacterial macromolecules in mucosal epithelial cells drive inflammatory signaling, offering new insights into microbial-host interactions and their potential impact on inflammatory disease treatment and drug efficacy.
npj Biofilms and Microbiomes · Jun 10, 2025Peer-reviewedCell Biology