Author

Hyun Koo

University of PennsylvaniaORCID 0000-0001-9143-2076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adam J. KimpleiD· 1 shared Akira HasuikeiD· 1 shared Aleksandra TataiD· 1 shared Ameer GhodkeiD· 1 shared Andrea C. KianiD· 1 shared Andrew D. A. MaidmentiD· 1 shared Andrew R. HannaiD· 1 shared Brittany RuppiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Adam J. KimpleORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 12, 2026

Emulating the gingival-tooth interface during bacterial, fungal, and viral infection in a microphysiological model of the human oral cavity

Mousa Younesi, Pouria Fattahi, Zhi Ren…·Dongeun Huh

This study develops a microphysiological model of the human oral cavity to study host-microbe interactions during bacterial, fungal, and viral infections.

DOI 10.64898/2026.06.11.731421

humanscRNA-seq

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BioengineeringScientific ReportsPeer-reviewedFeb 26, 2026

Scalable flow synthesis of ultrasmall inorganic nanoparticles for biomedical applications via a confined impinging jet mixer

Andrea C. Kian, Mahima Gupta, Heeju Hong…·David P. Cormode

This paper develops a scalable method to produce ultrasmall inorganic nanoparticles for biomedical use using a confined impinging jet mixer.

DOI 10.1038/s41598-026-41509-z

experimental assay

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Cell Biologynpj Biofilms and MicrobiomesPeer-reviewedJun 10, 2025

Polybacterial Intracellular Macromolecules Shape Single-Cell Epikine Profiles in Upper Airway Mucosa

Quinn T. Easter, Zabdiel Alvarado‐Martinez, Meik Kunz…·Kevin M. Byrd

This study reveals how persistent intracellular bacterial macromolecules in mucosal epithelial cells drive inflammatory signaling, offering new insights into microbial-host interactions and their potential impact on inflammatory disease treatment and drug efficacy.

4 citations

humanscRNA-seq

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