Deletion of Robo4 worsens neuroinflammation and motor coordination in a mouse model of Alzheimer's disease
Abigail E. Cullen, Nick R. Winder, Byron Lee, Sahana Krishna Kumaran, Nayantara Arora, Julia R. Wolf, Grant D. Henson, Randall L. Woltjer, Ashley E. Walker
This study shows that Robo4 deletion increases neuroinflammation and impairs motor coordination in Alzheimer's disease mice, with effects dependent on AD mutations and brain region.
Physiological Reports · Jun 1, 2026Peer-reviewedPhysiology