Klf5 establishes bi-potential cell fate by dual regulation of ICM and TE specification genes
Martin Kinisu, Yong Jin Choi, Claudia Cattoglio, Ke Liu, Hector Roux de Bézieux, Raeline Valbuena, Nicole Pum, Sandrine Dudoit, Haiyan Huang, Zhenyu Xuan, Sang Yong Kim, Lin He
This study identifies Klf5 as a key regulator of bi-potential cell fate in mouse preimplantation embryos by controlling both ICM and TE specification genes.
Cell Reports · Nov 1, 2021Peer-reviewedDevelopmental Biology