Haiyan Huang

Large-Scale Information Retrieval and Correction of Noisy Pharmacogenomic Datasets through Residual Thresholded Deep Matrix Factorization

This paper introduces RT-DMF, a deep learning framework to correct noise and impute missing values in pharmacogenomic datasets, improving downstream analysis.

Mechanism of ZNF143 in chromatin looping and 3D genome organization

This study identifies ZNF143's role in chromatin looping and 3D genome organization by showing its directional recognition of genomic sites and collaboration with CTCF.

Streamline unsupervised machine learning to survey and graph indel-based haplotypes from pan-genomes

The paper develops BRIDGEcereal, a web tool using unsupervised machine learning to survey and graph indel-based haplotypes from pan-genomes, demonstrating its use in wheat candidate genes.

Klf5 establishes bi-potential cell fate by dual regulation of ICM and TE specification genes

This study identifies Klf5 as a key regulator of bi-potential cell fate in mouse preimplantation embryos by controlling both ICM and TE specification genes.