Author

Nicole Rimann

University Children's Hospital Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1

Frequent Co-Authors

Beat ThönyiD· 3 shared Gerald SchwankiD· 3 shared Hiu Man Grisch‐ChaniD· 3 shared Tanja RothgangliD· 3 shared Eleonora I. IoannidiiD· 2 shared Martina Hruzova· 2 shared Anja A. WolfiD· 1 shared Christian KupattiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Beat ThönyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapeutic liver cell transplantation to treat a genetic liver defect

Melanie Willimann, Hiu Man Grisch‐Chan, Nicole Rimann, Tanja Rothgangl, Martina Hruzova, Gerald Schwank, Beat Thöny

This paper describes a gene therapy approach using liver cell transplantation to treat PKU in mice by modifying hepatocytes to resist paracetamol and replace diseased cells.

bioRxiv · Jun 26, 2024 · PreprintMolecular Biology

Safe delivery of AAV vectors to the liver of small weaned pigs by ultrasound guided percutaneous transhepatic portal vein injection

Tanja Rothgangl, Martina Hruzova, Ralph Gnannt, Nadja Aeberhard, Lucas Kissling, Hiu Man Grisch‐Chan, Sven Klassa, Nicole Rimann, Kim Fabiano Marquart, Eleonora I. Ioannidi, Anja A. Wolf, Christian Kupatt, Xaver Sidler, Johannes Häberle, Gerald Schwank, Beat Thöny

The paper describes a minimally invasive method for delivering AAV vectors to pig livers but finds low vector retention and no detectable editing in vivo.

bioRxiv · Apr 5, 2023 · PreprintMolecular Biology

Treatment of a metabolic liver disease by in vivo prime editing in mice

Desirée Böck, Tanja Rothgangl, Lukas Villiger, Lukas Schmidheini, Nicholas Mathis, Eleonora I. Ioannidi, Susanne Kreutzer, Zacharias Kontarakis, Nicole Rimann, Hiu Man Grisch‐Chan, Beat Thöny, Gerald Schwank

In vivo prime editing corrects phenylketonuria in mice by repairing the Pah gene mutation and reducing blood phenylalanine levels.

bioRxiv · Aug 17, 2021 · PreprintGenetics