The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ
Peter R. Martin, Jadwiga Nieminuszczy, Zuza Kozik, Nihal Jakub, Maxime Lecot, Julia Vorhauser, Karen A. Lane, Αλεξάνδρα Κανέλλου, Jörg Mansfeld, Laurence H. Pearl, Antony W. Oliver, Jessica A. Downs, Jyoti Sharma Choudhary, M.W. Day, Wojciech Niedźwiedź
The paper identifies the CIP2A-TOPBP1 axis as a regulator of mitotic DNA repair pathways, showing it promotes MiDAS and MMEJ through distinct mechanisms.
bioRxiv · Nov 12, 2024 · PreprintMolecular Biology