M.W. Day

This study identifies how the BTRR complex assembles on ultrafine DNA bridges through SLiM recognition by RMI1-RMI2, revealing spatiotemporal regulation during DNA repair and segregation.

The paper studies how duplicated odorant receptor genes in Drosophila gain new expression in olfactory sensory neurons, showing evolutionary recoding without new neuron lineages.

The paper shows that Ska and Ndc80 complexes form oligomers to stabilize microtubule ends during mitosis, with a mutation disrupting Ska:Ska interactions and impairing stability.

This study identifies a centromere protection pathway in human mitotic cells that relies on strict mitotic inactivation of the BTRR complex through phosphorylation and kinase regulation.

The paper identifies RIF1-Long as a BRCA1 binding partner that enhances RAD51-dependent repair during DNA replication stress.

The paper identifies the CIP2A-TOPBP1 axis as a regulator of mitotic DNA repair pathways, showing it promotes MiDAS and MMEJ through distinct mechanisms.

This study shows TopBP1 interacts with GINS via two distinct sites to support replication origin firing and predicts coordination of molecular processes in origin activation.

This paper shows that CK2 phosphorylation of HPV16 E2 on serine 23 promotes interaction with TopBP1, which is critical for plasmid retention and HPV16 immortalization of keratinocytes.