Author

Noor Kundu

Sunnybrook Health Science Centre

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adam DowleiD· 1 shared Alexandra Misura· 1 shared Andrew N. HoldingiD· 1 shared August LiniD· 1 shared David KealyiD· 1 shared Dianne E. Chadwick· 1 shared Dylan Gowlett-ParkiD· 1 shared Emily TsaoiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperCancer Biology

Adam DowleORCID

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1 paper

Recent·Most cited

Cancer BiologyBloodPeer-reviewedJun 20, 2026

Aberrant splicing of MBD1 reshapes the epigenome to drive convergent myeloerythroid defects in MDS

He Tian Chen, Pratik Joshi, Séverine Cathelin…·Kristin J. Hope

This study identifies MBD1-L, an aberrantly spliced transcript in MDS, which drives epigenetic changes leading to myeloerythroid defects, and shows ASO-based targeting can restore erythroid differentiation.

2 citationstop 4%

humanbulk RNA-seq

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