MicroRNA regulation of the MRN complex impacts DNA damage, cellular senescence and angiogenic signaling
C. Espinosa-Diez, R. Wilson, N. Chatterjee, C. Hudson, R. Ruhl, C. Hipfinger, E. Helms, O. F. Khan, D. G. Anderson, S. Anand
The paper shows that miR-494 and miR-99b regulate the MRN complex, affecting DNA repair, senescence, and angiogenesis through VEGF and CD44 pathways.
bioRxiv · Jan 18, 2018Cancer Biology