Author

O. Le

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1

Frequent Co-Authors

C. Beausejour· 2 shared G. Moquin-Beaudry· 2 shared A. Sonn· 1 shared B. Benabdalah· 1 shared B. Benabdallah· 1 shared B. Ellezam· 1 shared C. Colas· 1 shared C. Raggi· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Beausejour

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Senescent human fibroblasts have increased FasL expression and impair the tumor immune response

M. Cruz, J. Dulong, G. Mansour Nehmo, A. Sonn, G. Moquin-Beaudry, B. Benabdallah, O. Le, C. Beausejour

The paper shows senescent human fibroblasts increase FasL expression, leading to T and NK cell apoptosis and impaired tumor immune response in humanized models.

bioRxiv · Jun 10, 2024 · PreprintCancer Biology

Autologous humanized mouse models of iPSC-derived tumors allow for the evaluation and modulation of cancer-immune cell interactions

G. Moquin-Beaudry, B. Benabdalah, D. Maggiorani, O. Le, Y. Li, C. Colas, C. Raggi, B. Ellezam, M. M'Callum, D. Dal Soglio, J. V. Guimond, M. Paganelli, E. Haddad, C. Beausejour

This paper develops autologous humanized mouse models of iPSC-derived tumors to study and modulate cancer-immune interactions, showing immune infiltration and response to PD-1 inhibition.

bioRxiv · Apr 2, 2021Cancer Biology