Author

O. M. Dovey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

G. Giotopoulos· 2 shared G. S. Vassiliou· 2 shared M. Gozdecka· 2 shared A. Castillo-Venzor· 1 shared A. F. Domingues· 1 shared A. Mupo· 1 shared B. Huntly· 1 shared B. J. P. Huntly· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

G. Giotopoulos

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Optimised whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells

S. Usluer, P. Hallast, L. Crepaldi, Y. Zhou, K. Urgo, C. Dincer, J. Su, G. Noell, K. Alasoo, O. El Garwany, S. Gerety, B. Newman, O. M. Dovey, L. Parts

The paper optimizes CRISPR interference screens in human iPSCs using dCas9-KRAB-MeCP2, identifies ARID1A-dependent growth regulators, and finds proteasome-related genes as synthetic lethal targets.

bioRxiv · Oct 3, 2022 · PreprintCell Biology

Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis

S. Gupta, O. M. Dovey, A. F. Domingues, O. W. Cyran, C. M. Cash, G. Giotopoulos, J. Rak, J. Cooper, M. Gozdecka, R. J. Asby, N. Al-Jabery, V. Hernandez-Hernandez, S. Prabakaran, B. Huntly, G. S. Vassiliou, C. Pina

Loss of Kat2a enhances transcriptional variability of ribosome biosynthetic programs and transiently accelerates pre-leukemia.

bioRxiv · Oct 18, 2021 · PreprintCancer Biology

Mutational synergy coordinately remodels chromatin accessibility, enhancer landscape and 3-Dimensional DNA topology to alter gene expression during leukemia induction

H. Yun, S. Vohra, A. Mupo, G. Giotopoulos, D. Sasca, S. J. Horton, S. Agrawal-Singh, E. Meduri, F. Basheer, L. Marando, M. Gozdecka, O. M. Dovey, A. Castillo-Venzor, X. Wang, P. Gallipoli, , B. J. P. Huntly

The paper investigates how mutations synergize to alter chromatin accessibility, enhancer landscapes, and 3D DNA topology in leukemia induction using a murine model.

bioRxiv · Mar 20, 2020Cancer Biology