Author

O. V. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. I. Kotov· 2 shared D. L. Jaye· 2 shared R. E. Vance· 2 shared A. Moon· 1 shared B. A. Rosa· 1 shared B. D. Bryson· 1 shared C. Gabay· 1 shared C. Langner· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

D. I. Kotov

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Interleukin-1 receptor antagonist is a conserved factor for exacerbating tuberculosis susceptibility

O. V. Lee, E. Pathak, S. Hernandez-Bazan, D. X. Ji, B. A. Rosa, D. L. Jaye, S. Suliman, M. Mitreva, C. Gabay, R. E. Vance, D. I. Kotov

The paper identifies IL-1 receptor antagonist as a conserved factor limiting Mtb control across mice, non-human primates, and humans.

bioRxiv · Oct 27, 2023 · PreprintImmunology

Early cellular mechanism of type I interferon-driven susceptibility to tuberculosis

D. I. Kotov, O. V. Lee, S. A. Fattinger, C. Langner, J. V. Guillen, J. M. Peters, A. Moon, E. M. Burd, K. C. Witt, D. B. Stetson, D. L. Jaye, B. D. Bryson, R. E. Vance

This study identifies interstitial macrophages and plasmacytoid dendritic cells as key producers of type I IFN during Mtb infection, showing their role in driving tuberculosis pathogenesis through IFN-driven mechanisms.

bioRxiv · Oct 6, 2022Immunology