A Comprehensive Atlas of AAV Tropism in the Mouse
Christopher J. Walkey, Kathy J. Snow, Jote Bulcha, Aaron R. Cox, Alexa E. Martinez, M. Cecilia Ljungberg, Denise Grant Lanza, Marco De Giorgi, Marcel A. Chuecos, Michele Alves‐Bezerra, Carlos Perfecto Flores Suarez, Sean Michael Hartig, Susan Galloway Hilsenbeck, Chih‐Wei Hsu, Ethan Saville, , William R. Lagor
This paper maps the tissue tropism of ten AAV serotypes in mice after systemic delivery, identifying liver preference and unexpected transduction in adrenals, testes, and ovaries.
Molecular Therapy · Jan 25, 2025Peer-reviewedMolecular Biology