M. Cecilia Ljungberg

This study identifies a common inhibitory cortical circuit disruption in two genetically distinct absence epilepsy mouse models that leads to seizure onset.

This study shows common AAV vectors transduce multiple human brain cell types in organotypic slices, with astrocytes showing the most protein expression, and introduces a pipeline for optimizing AAV vectors.

This paper introduces a method to increase the proportion of correctly repaired hepatocytes in the liver through transient gene inhibition and transgene delivery, achieving a 25% increase in targeted cells and five-fold transgene expression.

This paper maps the tissue tropism of ten AAV serotypes in mice after systemic delivery, identifying liver preference and unexpected transduction in adrenals, testes, and ovaries.

The paper identifies molecular logic underlying cellular specializations in the cochlear nuclear complex using single-nucleus RNA sequencing and Patch-seq.

The paper shows SOX7 deficiency causes ventricular septal defects by impairing endocardial-to-mesenchymal transition through reduced Wnt4 and Bmp2 expression in developing atrioventricular canals.