Author

Oliver B Nicholson

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Christopher P. LapointeiD· 2 shared Arvind Rasi SubramaniamiD· 1 shared Carlos AlvaradoiD· 1 shared Heungwon ParkiD· 1 shared Ivaylo P. IvanoviD· 1 shared Joseph Daniel PuglisiiD· 1 shared Rachael A. Bakker· 1 shared Rosslyn Grosely· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Christopher P. LapointeORCID

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2 papers

Recent·Most cited

eIF1 and eIF5 dynamically control translation start site fidelity

Rosslyn Grosely, Carlos Alvarado, Ivaylo P. Ivanov, Oliver B Nicholson, Joseph Daniel Puglisi, Thomas E. Dever, Christopher P. Lapointe

This study investigates how eIF1 and eIF5 dynamically regulate translation start site fidelity through single-molecule analysis and cell experiments.

Nature Structural & Molecular Biology · Jul 28, 2025Peer-reviewedBiophysics

Deaminase-based RNA recording enables high throughput mutational profiling of protein-RNA interactions

Rachael A. Bakker, Oliver B Nicholson, Heungwon Park, Yu‐Lan Xiao, Weixin Tang, Arvind Rasi Subramaniam, Christopher P. Lapointe

This paper uses a deaminase-based RNA recording method to profile protein-RNA interactions by introducing nucleotide edits detectable via DNA sequencing, revealing conserved sequence requirements across different contexts.

bioRxiv · Apr 11, 2025 · PreprintMolecular Biology