Weixin Tang

This paper introduces RAD-seq, a method to quantify RNA accessibility by protein binding, and shows it can detect RBP footprints and RNA structure changes under stress.

This study shows that Pseudomonas aeruginosa inactivates its type I R-M system via proteolysis at high temperatures, leading to prolonged genomic hypomethylation and a memory effect lasting over 60 generations.

The paper identifies cognate recombination directionality factors (RDFs) for large serine recombinases using AlphaFold2-multimer and experimental validation.

The paper introduces eTAM-seq-v2, an improved method for m6A profiling with higher fidelity and lower input requirements, and applies it to human cells and mouse tissues.

This paper uses a deaminase-based RNA recording method to profile protein-RNA interactions by introducing nucleotide edits detectable via DNA sequencing, revealing conserved sequence requirements across different contexts.