Author
Broad InstituteORCID 0000-0001-5975-880XUnclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Perry W.E. Spratt, Nicholas F. Trojanowski, Rajani M. George…·Kathryn C. Allaway
This study uses CRISPR activation to upregulate SCN1A in PV interneurons, improving survival and reducing seizures in Dravet syndrome models.
Kathryn C. Allaway, William Muñoz, Robin Tremblay…·Gord Fishell
The paper shows that cellular birthdate determines laminar and regional specificity of cholinergic projections in the forebrain.
Douglas Vormstein-Schneider, Jessica D. Lin, Kenneth A. Pelkey…·Jordane Dimidschstein
The paper identifies enhancers for targeting specific neuronal subtypes across species and demonstrates their utility in circuit manipulation.
Mariano I. Gabitto, Anders W. Rasmussen, Orly L. Wapinski…·Richard Bonneau
The paper introduces ChromA, a Bayesian method for analyzing ATAC-seq data to annotate chromatin accessibility, improving cell type identification and correcting biases in single-cell data.
Christian Mayer, Christoph Hafemeister, Rachel C. Bandler…·Rahul Satija
The paper uses single-cell RNA-seq to study the development of cortical interneurons, identifying key transcription factors and cell states involved in their diversification.