Author

Ossama Ghenissa

Centre Hospitalier de l’Université de Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ciaran Murphy‐RoyaliD· 2 shared Manon DuquenneiD· 2 shared Mathias GuayasaminiD· 2 shared Sarah Peyrard· 2 shared Anthony BossoniD· 1 shared Bénédicte AmilhoniD· 1 shared Benjamin Rogers· 1 shared Ifeoluwa I Adedipe· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Ciaran Murphy‐RoyalORCID

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2 papers

Recent·Most cited

Astrocytic Encoding of Threat in the Basolateral Amygdala

Ossama Ghenissa, Mathias Guayasamin, Kathleen Ngo, Manon Duquenne, Sarah Peyrard, Bénédicte Amilhon, Ciaran Murphy‐Royal

The paper shows that astrocytes in the basolateral amygdala encode threat-induced anxiety across tasks, contrasting with neurons that encode broader behavioral states.

Neuron · Mar 24, 2026Peer-reviewedNeuroscience

Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation

Mathias Guayasamin, Lewis R Depaauw-Holt, Ifeoluwa I Adedipe, Ossama Ghenissa, Juliette Vaugeois, Manon Duquenne, Benjamin Rogers, Jade Latraverse-Arquilla, Sarah Peyrard, Anthony Bosson, Ciaran Murphy‐Royal

This study shows early-life stress causes astrocyte dysfunction in mice, leading to anxiety and fear generalization through impaired synaptic plasticity and neural excitability.

bioRxiv · Dec 11, 2022Neuroscience