Author

Sarah Peyrard

Centre Hospitalier de l’Université de Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:electronic health records· 2 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Ciaran Murphy-RoyaliD· 4 shared Anthony BossoniD· 3 shared Manon DuquenneiD· 3 shared Mathias GuayasaminiD· 3 shared Benjamin Rogers· 2 shared Kathleen NgoiD· 2 shared Lewis R Depaauw-HoltiD· 2 shared Ossama Ghenissa· 2 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Ciaran Murphy-RoyalORCID

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5 papers

Recent·Most cited

Sex-dependent and region-specific morphological adaptations in astrocytes following early-life stress

Camila Cabarcas Arrieta, Anthony Bosson, Mathias Guayasamin, Kathleen Ngo, Sarah Peyrard, Ciaran Murphy-Royal

This study uses sparse eGFP labeling to compare astrocyte morphology across brain regions and sexes in mice, finding sex-dependent and region-specific changes after early-life stress.

bioRxiv · Nov 6, 2026 · PreprintNeuroscience

TDP-43 pathology is linked to motor neuron loss and is independent of stress granules in vivo

Alicia F. Dubinski, Ala Ferdi, Mariam Choughari, Holly Spence, Arpita Adhikary, Carolane Fauchon, Melissa Touati, Myriam Gagné, Martha Liu, Sarah Peyrard, Jenna Gregory, Christine Vande Velde

This study shows TDP-43 pathology occurs independently of stress granules in motor neurons, challenging existing models of TDP-43 pathogenesis.

bioRxiv · Apr 14, 2026 · PreprintNeuroscience

Astrocytic Encoding of Threat in the Basolateral Amygdala

Ossama Ghenissa, Mathias Guayasamin, Kathleen Ngo, Manon Duquenne, Sarah Peyrard, Bénédicte Amilhon, Ciaran Murphy‐Royal

The paper shows that astrocytes in the basolateral amygdala encode threat-induced anxiety across tasks, contrasting with neurons that encode broader behavioral states.

Neuron · Mar 24, 2026Peer-reviewedNeuroscience

Astrocyte glucocorticoid receptors mediate sex-specific changes in activity following stress

Lewis R Depaauw-Holt, Manon Duquenne, Sarah Hamane, Sarah Peyrard, Benjamin Rogers, Clara Ireland, Yusuke Nasu, Stephanie E. Fulton, Anthony Bosson, Thierry Alquier, Ciaran Murphy‐Royal

The paper investigates how stress affects activity levels through interactions between orexin neurons and astrocytes, finding that astrocytic glucocorticoid receptors mediate sex-specific changes in neuronal firing and activity.

Nature Communications · Jul 10, 2025Peer-reviewedNeuroscience

Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation

Mathias Guayasamin, Lewis R Depaauw-Holt, Ifeoluwa I Adedipe, Ossama Ghenissa, Juliette Vaugeois, Manon Duquenne, Benjamin Rogers, Jade Latraverse-Arquilla, Sarah Peyrard, Anthony Bosson, Ciaran Murphy‐Royal

This study shows early-life stress causes astrocyte dysfunction in mice, leading to anxiety and fear generalization through impaired synaptic plasticity and neural excitability.

bioRxiv · Dec 11, 2022Neuroscience