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Oxford Acute Myocardial Infarction Study

University of Oxford

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Pathology· 1

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea D. van Dam· 1 shared Christoph ThiemermanniD· 1 shared David R. GreavesiD· 1 shared Gareth S. D. PurvisiD· 1 shared Giacomo EinaudiiD· 1 shared Keith M. ChannoniD· 1 shared Massimo CollinoiD· 1 shared Mayooran ShanmuganathaniD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

Andrea D. van Dam

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1 paper

Recent·Most cited

PathologyDiabetesPeer-reviewedJan 8, 2024

OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity

Gareth S. D. Purvis, Massimo Collino, Andrea D. van Dam…·David R. Greaves

This paper shows that inhibiting BTK in adipose tissue macrophages enhances OxPhos and shifts macrophages to an M2-like state, reducing inflammation and improving metabolic outcomes in obesity.

10 citations

mouseproteomics

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