Author

Mayooran Shanmuganathan

John Radcliffe HospitalORCID 0000-0001-8036-6253Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea D. van Dam· 1 shared Christoph ThiemermanniD· 1 shared David R. GreavesiD· 1 shared Gareth S. D. PurvisiD· 1 shared Giacomo EinaudiiD· 1 shared Keith M. ChannoniD· 1 shared Massimo CollinoiD· 1 shared Oxford Acute Myocardial Infarction Study· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

Andrea D. van Dam

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1 paper

Recent·Most cited

PathologyDiabetesPeer-reviewedJan 8, 2024

OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity

Gareth S. D. Purvis, Massimo Collino, Andrea D. van Dam…·David R. Greaves

This paper shows that inhibiting BTK in adipose tissue macrophages enhances OxPhos and shifts macrophages to an M2-like state, reducing inflammation and improving metabolic outcomes in obesity.

10 citations

mouseproteomics

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