WAVE complex self-organization templates lamellipodial formation
A. Pipathsouk, R. M. Brunetti, J. P. Town, A. Breuer, P. A. Pellett, K. Marchuk, N.-H. T. Tran, M. F. Krummel, D. Stamou, O. D. Weiner
The paper investigates how the WAVE complex self-organizes into linear structures to form lamellipodia, contrasting with N-WASP's spiky actin networks, and shows how curvature sensing enables cell shape regulation.
bioRxiv · Nov 9, 2019 · PreprintCell Biology