Author

J. P. Town

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

O. D. Weiner· 4 shared A. Breuer· 1 shared A. Diz-Munoz· 1 shared A. Iglic· 1 shared A. Pipathsouk· 1 shared B. R. Graziano· 1 shared C. J. Bustamante· 1 shared D. Stamou· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersCell Biology

O. D. Weiner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Rac negative feedback links local PIP3 rate-of-change to dynamic control of neutrophil guidance

J. P. Town, O. D. Weiner

The paper investigates how Rac negative feedback modulates neutrophil guidance by linking local PIP3 rate-of-change to dynamic control of cell polarization.

bioRxiv · Dec 30, 2022 · PreprintCell Biology

Actin-driven protrusions generate rapid long-range membrane tension propagation in cells

H. De Belly, S. Yan, H. Borja da Rocha, S. Ichbiah, J. P. Town, H. Turlier, C. J. Bustamante, O. D. Weiner

The paper uses optogenetics and optical tweezers to show that actin-driven protrusions enable rapid, long-range membrane tension propagation, contrasting with localized force application.

bioRxiv · Sep 7, 2022 · PreprintCell Biology

WAVE complex self-organization templates lamellipodial formation

A. Pipathsouk, R. M. Brunetti, J. P. Town, A. Breuer, P. A. Pellett, K. Marchuk, N.-H. T. Tran, M. F. Krummel, D. Stamou, O. D. Weiner

The paper investigates how the WAVE complex self-organizes into linear structures to form lamellipodia, contrasting with N-WASP's spiky actin networks, and shows how curvature sensing enables cell shape regulation.

bioRxiv · Nov 9, 2019 · PreprintCell Biology

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

B. R. Graziano, J. P. Town, T. L. Nagy, M. Fosnaric, S. Penic, A. Iglic, V. Kralj-Iglic, N. Gov, A. Diz-Munoz, O. D. Weiner

This study shows that neutrophils can maintain polarity and movement without branched actin networks when confined, revealing a bleb-based protrusion mechanism distinct from the conventional actin-based one.

PLOS Biology · Oct 10, 2019Peer-reviewedCell Biology