Author

P. Agnihotri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. K. Andrianov· 1 shared A. Marin· 1 shared B. Pierce· 1 shared C. Zhu· 1 shared E. A. Toth· 1 shared F. Griffitts· 1 shared H.-K. Choi· 1 shared J. D. Guest· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. K. Andrianov

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2 papers

Recent·Most cited

Cooperative binding of TCR and CD4 to pMHC enhances TCR sensitivity

M. N. Rushdi, V. Pan, K. Li, H.-K. Choi, S. Choi, J. Hong, F. Griffitts, P. Agnihotri, R. A. Mariuzza, Y. Ke, C. Zhu

The paper shows CD4 enhances TCR sensitivity by forming trimolecular bonds with pMHC, which are stabilized by force and proximity.

bioRxiv · Nov 22, 2021 · PreprintImmunology

Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization

B. Pierce, Z.-y. Keck, R. Wang, P. Lau, K. J. Garagusi, K. Elkholy, E. A. Toth, R. A. Urbanowicz, J. D. Guest, P. Agnihotri, M. C. Kerzic, A. Marin, A. K. Andrianov, J. K. Ball, R. Mariuzza, , S. Foung

The paper designs optimized HCV E2 glycoproteins to enhance binding and cross-neutralization by modifying antigenic sites and testing immunogenicity in mice.

bioRxiv · Apr 15, 2020Microbiology