Author

J. K. Ball

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

R. A. Urbanowicz· 3 shared T. Tsoleridis· 3 shared A. Folgori· 1 shared A. G. Pockley· 1 shared A. K. Andrianov· 1 shared A. Lahm· 1 shared A. Leuzzi· 1 shared A. M. Contino· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

R. A. Urbanowicz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

In vitro evolution predicts emerging CoV-2 mutations with high affinity for ACE2 and cross-species binding

N. Bate, C. G. Savva, P. C. Moody, E. A. Brown, J. K. Ball, J. W. Schwabe, J. Sale, N. Brindle

The paper uses in vitro evolution to identify CoV-2 mutations that enhance ACE2 binding and cross-species transmission, finding mutations like Q498H and Q498R/N501Y that are emerging in variants like Omicron.

bioRxiv · Dec 23, 2021Biochemistry

SARS-CoV-2 spike RBD and nucleocapsid encoding DNA vaccine elicits T cell and neutralising antibody responses that cross react with variants

V. A. Brentville, M. Vankemmelbeke, R. L. Methingham, P. Symonds, K. W. Cook, R. A. Urbanowicz, T. Tsoleridis, C. M. Coleman, K.-C. Chang, A. Skinner, E. Dubinina, I. Daniels, S. Shah, M. Argonza, J. Delgado, , L. G. Durrant

This paper designs a DNA vaccine encoding SARS-CoV-2 spike RBD and nucleocapsid proteins, showing strong T cell responses and cross-reactive neutralizing antibodies against variants in mice.

bioRxiv · Jun 18, 2021 · PreprintImmunology

Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19

A. Vitelli, S. Capone, A. Raggioli, M. Gentile, S. Battella, A. Lahm, A. Sommella, A. M. Contino, R. A. Urbanowicz, R. Scala, F. Barra, A. Leuzzi, E. Lilli, G. Miselli, A. Noto, , S. Colloca

This paper evaluates a gorilla adenovirus vaccine candidate for COVID-19, showing it is immunogenic in mice and macaques and supports its advancement to a Phase I clinical trial.

bioRxiv · Oct 22, 2020Immunology

Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization

B. Pierce, Z.-y. Keck, R. Wang, P. Lau, K. J. Garagusi, K. Elkholy, E. A. Toth, R. A. Urbanowicz, J. D. Guest, P. Agnihotri, M. C. Kerzic, A. Marin, A. K. Andrianov, J. K. Ball, R. Mariuzza, , S. Foung

The paper designs optimized HCV E2 glycoproteins to enhance binding and cross-neutralization by modifying antigenic sites and testing immunogenicity in mice.

bioRxiv · Apr 15, 2020Microbiology

Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports its Classification as a Novel Species

J. G. Chappell, T. Tsoleridis, O. Onianwa, P. Dobbs, G. Drake, I. Ashpole, W. Edema, F. Kumi-Ansah, M. Bennett, R. E. Tarlinton, J. K. Ball, C. P. McClure

bioRxiv · Nov 16, 2019Microbiology