Modelling cancer immunomodulation using epithelial organoid cultures
Y. E. Bar-Ephraim, K. Kretzschmar, P. Asra, E. de Jongh, K. E. Boonekamp, J. Drost, J. van Gorp, A. Pronk, N. Smakman, I. J. Gan, Z. Sebestyen, J. H. Kuball, R. G. Vries, H. Clevers
This study uses CRC organoids to model immune-cancer interactions and assess immunomodulation by co-culturing with cytotoxic T cells.
bioRxiv · Oct 4, 2018 · PreprintCancer Biology