Author

P. Asthana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. K. Ecker· 1 shared A. V. Murthy· 1 shared B. Faust· 1 shared D. Singh· 1 shared G. J. Correy· 1 shared I. B. Seiple· 1 shared I. D. Young· 1 shared J. Jänis· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. K. Ecker

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2 papers

Recent·Most cited

Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

R. E. Diaz, A. K. Ecker, G. J. Correy, P. Asthana, I. D. Young, B. Faust, M. C. Thompson, I. B. Seiple, S. J. Van Dyken, R. M. Locksley, J. S. Fraser

This study characterizes the pH-specific enzymatic activity and ligand binding of mouse AMCase using structural and computational methods, revealing dual activity optima at pH 2 and 7.

bioRxiv · Jun 3, 2023Biochemistry

Structural insights on the substrate-binding proteins of the Mycobacterium tuberculosis mammalian-cell-entry (Mce) 1 and 4 complexes

P. Asthana, D. Singh, J. S. Pedersen, M. J. Hynönen, R. Sulu, A. V. Murthy, M. Laitaoja, J. Jänis, L. W. Riley, R. Venkatesan

This study reports the structural properties of Mce substrate-binding proteins from Mycobacterium tuberculosis, revealing a novel heterohexameric arrangement and domain-specific interactions.

bioRxiv · Sep 29, 2020Biophysics