Author

P. Bhadra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Organism:yeast· 1

Frequent Co-Authors

V. Helms· 2 shared A. Boergel· 1 shared A. Cavalie· 1 shared B. S. Hall· 1 shared F. Stengel· 1 shared G. Barbieri· 1 shared I. Gamayun· 1 shared J. Ogbechi· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

V. Helms

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2 papers

Recent·Most cited

Sbh1/Sec61beta is a specific signal peptide receptor within the Sec61 channel

L. Yadhanapudi, M. Lommel, P. Bhadra, G. Barbieri, R. Singh, M. Jung, V. Helms, T. Eisgruber, F. Stengel, A. Boergel, K. Remans, K. Romisch

This study identifies Sbh1/Sec61β as a specific signal peptide receptor that recognizes and guides substrates into the Sec61 channel through its cytosolic IDR and conserved regions.

bioRxiv · Mar 12, 2024 · PreprintBiochemistry

Mycolactone enhances the Ca2+ leakage from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state

P. Bhadra, S. Dos Santos, I. Gamayun, T. Pick, J. Ogbechi, B. S. Hall, R. Zimmermann, V. Helms, R. E. Simmonds, A. Cavalie

This study shows mycolactone enhances Ca2+ leakage from the ER by trapping Sec61 translocons in a Ca2+ permeable state, leading to ER Ca2+ depletion.

bioRxiv · May 12, 2021Biochemistry