Author

P. Castagnino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Basu· 2 shared E. A. White· 2 shared H. W. Kim· 2 shared J. Hatterschide· 1 shared K. T. Montone· 1 shared L. K. M. Lam· 1 shared S. M. Sperry· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

D. Basu

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Author profile →

2 papers

Recent·Most cited

Systematic analysis of IL-1 cytokine signaling suppression by high-risk HPV oncoproteins

P. Castagnino, H. W. Kim, L. K. M. Lam, D. Basu, E. A. White

This study shows that HPV16 E6 and E7 oncoproteins suppress IL-1β signaling in both early and late stages of HPV-induced carcinogenesis by upregulating suppressors like SIGIRR.

bioRxiv · Aug 25, 2022Microbiology

YAP1 Activation by Human Papillomavirus E7 Promotes Basal Cell Identity in Squamous Epithelia

J. Hatterschide, P. Castagnino, H. W. Kim, S. M. Sperry, K. T. Montone, D. Basu, E. A. White

This study shows that HPV E7 activates YAP1, promoting basal cell identity and contributing to HPV persistence and carcinogenesis.

bioRxiv · Nov 10, 2021Microbiology