Author

P. De Ioannes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:ChIP-seq· 2 Organism:human· 2 Assay:DNA methylation· 1 Organism:virus· 1

Frequent Co-Authors

K.-J. Armache· 3 shared C. Lu· 2 shared E. Nudler· 2 shared K. Gretarsson· 2 shared M. I. Valencia-Sanchez· 2 shared R. Lee· 2 shared S. Abini-Agbomson· 2 shared A. R. Hickman· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBiochemistry

K.-J. Armache

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Author profile →

3 papers

Recent·Most cited

Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1

S. Abini-Agbomson, K. Gretarsson, R. M. Shih, L. Hsieh, T. Lou, P. De Ioannes, N. Vasilyev, R. Lee, M. Wang, M. Simon, J.-P. Armache, E. Nudler, G. Narlikar, S. Liu, C. Lu, K.-J. Armache

This study characterizes the catalytic and non-catalytic mechanisms of SUV420H1 by determining cryo-EM structures and showing its role in DNA accessibility and chromatin condensation.

bioRxiv · Mar 17, 2023Biochemistry

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1

J. F. Thomas, M. I. Valencia-Sanchez, S. Tamburri, S. L. Gloor, S. Rustichelli, V. Godinez-Lopez, P. De Ioannes, R. Lee, S. Abini-Agbomson, K. Gretarsson, J. M. Burg, A. R. Hickman, L. Sun, S. Gopinath, H. Taylor, , K.-J. Armache

This study reveals the molecular mechanism of nucleosomal H2AK119Ub deubiquitination by human BAP1/ASXL1 and explains how cancer mutations disrupt this process.

bioRxiv · Feb 23, 2023Biochemistry

A giant virus genome is densely packaged by stable nucleosomes within virions

T. D. Bryson, P. De Ioannes, M. I. Valencia-Sanchez, J. G. Henikoff, P. B. Talbert, B. La Scola, K.-J. Armache, S. Henikoff

The paper shows that Marseillevirus uses fully wrapped nucleosomes to densely package its genome, differing from eukaryotic chromatin organization.

bioRxiv · Jan 15, 2022Evolutionary Biology