Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
S. Henikoff, Y. Zheng, R. M. Paranal, Y. Xu, J. E. Greene, J. G. Henikoff, Z. R. Russell, F. Szulzewsky, H. N. Thirimanne, S. Kugel, E. C. Holland, K. Ahmad
The paper identifies RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples, linking it to tumor progression and aneuploidy.
bioRxiv · Feb 28, 2024Cancer Biology
D. H. Janssens, M. Duran, D. J. Otto, W. Wu, Y. Xu, D. Kirkey, C. G. Mullighan, J. S. Yi, S. Meshinchi, J. F. Sarthy, K. Ahmad, S. Henikoff
This study shows KMT2A oncoproteins drive lineage-switching and epigenetic resistance in leukemia by dynamically binding chromatin and persisting as ENL-marked lesions despite therapy.
bioRxiv · Dec 29, 2023 · PreprintCancer Biology
S. Kaonis, J. L. Smith, N. Katiyar, M. Merrill, T. Hylkema, S. Namciu, Q. Le, E. Babaeva, T. Ikeda, S. M. Morris, E. Girard, S. Furuyama, R. Ries, I. Bernstein, S. Meshinchi, , J. F. Sarthy
This study identifies BRG1 inhibition as a therapeutic strategy for CBFA2T3-GLIS2 AML by analyzing chromatin profiles and CRISPR dependencies.
bioRxiv · Aug 30, 2023 · PreprintCancer Biology
S. Henikoff, J. G. Henikoff, K. Ahmad, R. M. Paranal, D. H. Janssens, Z. R. Russell, F. Szulzewsky, S. Kugel, E. C. Holland
This study modifies the CUTAC protocol to enable high-resolution epigenomic analysis of FFPE samples, identifying regulatory element differences in mouse brain tumors.
bioRxiv · Jun 20, 2023Cancer Biology
E. Hsieh, D. H. Janssens, P. J. Paddison, E. P. Browne, S. Henikoff, M. Ohainle, M. Emerman
This study uses a CRISPR screen to identify pathways involved in HIV-1 latency, finding that ING3 and AZD5582 combination activates proviruses.
bioRxiv · Aug 23, 2022Microbiology
N. De Sarkar, R. D. Patton, A.-L. Doebley, B. Hanratty, A. J. Kreitzman, J. F. Sarthy, M. Ko, M. Adil, S. Brahma, M. P. Meers, D. H. Janssens, L. S. Ang, I. Coleman, A. Bose, R. F. Dumpit, , G. Ha
This paper identifies nucleosome patterns in ctDNA that distinguish advanced prostate cancer phenotypes, achieving high accuracy in classification using a prediction model.
bioRxiv · Jun 21, 2022Cancer Biology
T. D. Bryson, P. De Ioannes, M. I. Valencia-Sanchez, J. G. Henikoff, P. B. Talbert, B. La Scola, K.-J. Armache, S. Henikoff
The paper shows that Marseillevirus uses fully wrapped nucleosomes to densely package its genome, differing from eukaryotic chromatin organization.
bioRxiv · Jan 15, 2022Evolutionary Biology
H. N. Thirmanne, F. Wu, D. H. Janssens, J. Swanger, H. Feldman, R. Amezquita, R. Gottardo, P. J. Paddison, S. Henikoff, B. E. Clurman
This study examines the transcriptional effects of Fbw7 mutations in colorectal cancer cells and identifies context-specific regulatory changes and co-regulated genes like CIITA.
bioRxiv · Oct 19, 2021Cancer Biology
H. Mathsyaraja, B. Freie, P.-F. Cheng, E. Babaeva, D. Janssens, S. Henikoff, R. N. Eisenman
The paper shows that deleting Max reduces MYC protein levels and prevents Eμ-Myc lymphomagenesis, but has minimal effect on B-cell development.
bioRxiv · Feb 21, 2019Cancer Biology