Author

P. Demetriou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. L. Dustin· 3 shared V. Mayya· 3 shared A. Siokis· 2 shared E. Abu-Shah· 2 shared M. A. Kutuzov· 2 shared M. Meyer-Hermann· 2 shared S. Valvo· 2 shared A. Kvalvaag· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

M. L. Dustin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In silico characterization of mechanisms positioning costimulatory and checkpoint complexes in immune synapses

A. Siokis, P. A. Robert, P. Demetriou, A. Kvalvaag, S. Valvo, V. Mayya, M. L. Dustin, M. Meyer-Hermann

The paper uses computer simulations to reveal how immunoglobulin superfamily adhesion and costimulatory/checkpoint complexes are localized in immunological synapses.

bioRxiv · Jan 16, 2020Immunology

A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells

E. Abu-Shah, P. Demetriou, S. Balint, V. Mayya, M. A. Kutuzov, O. Dushek, M. L. Dustin

This paper develops a tissue-like platform to study interactions between engineered quiescent human T-cells and dendritic cells, demonstrating CD4 help and PD-1 checkpoint blockade effects.

bioRxiv · Sep 12, 2019Immunology

CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation.

P. Demetriou, E. Abu-Shah, S. McCuaig, V. Mayya, S. Valvo, K. Korobchevskaya, M. Friedrich, E. Mann, L. Y. Lee, T. Starkey, M. A. Kutuzov, J. Afrose, A. Siokis, Oxford IBD Cohort Investigators, M. Meyer-Hermann, , M. L. Dustin

The paper shows CD2 expression levels determine immunological synapse structure and T-cell activation by influencing CD2-CD58 localization and Src-family kinase recruitment.

bioRxiv · Mar 29, 2019 · PreprintImmunology