Author

V. Mayya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 7 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 6 Research Focus:cell-cell communication· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1

Frequent Co-Authors

M. L. Dustin· 7 shared S. Valvo· 4 shared E. Abu-Shah· 3 shared P. Demetriou· 3 shared A. Siokis· 2 shared K. Korobchevskaya· 2 shared M. A. Kutuzov· 2 shared M. Meyer-Hermann· 2 shared

Activity by Year

2018-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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7 shared papersImmunology

M. L. Dustin

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

P. G. Cipriani, O. Bay, J. P. Zinno, M. Gutwein, H. H. Gan, V. Mayya, G. Chung, J. Chen, H. Fahs, Y. Guan, T. Duchaine, M. Selbach, F. Piano, K. Gunsalus

This study identifies MIP-1 and MIP-2 as C. elegans germ granule proteins that recruit Vasa homolog GLH-1 and are essential for granule formation and germ line development.

bioRxiv · Jun 17, 2021Cell Biology

In silico characterization of mechanisms positioning costimulatory and checkpoint complexes in immune synapses

A. Siokis, P. A. Robert, P. Demetriou, A. Kvalvaag, S. Valvo, V. Mayya, M. L. Dustin, M. Meyer-Hermann

The paper uses computer simulations to reveal how immunoglobulin superfamily adhesion and costimulatory/checkpoint complexes are localized in immunological synapses.

bioRxiv · Jan 16, 2020Immunology

Semaphorin 3A induces cytoskeletal paralysis in tumor-specific CD8+ T cells

M. B. Barnkob, Y. S. Michaels, V. Andre, P. S. Macklin, U. Gileadi, S. Valvo, M. Rei, C. Kulicke, J.-L. Chen, V. Jain, V. Woodcock, H. Colin-York, A. V. Hadjinicolaou, Y. Kong, V. Mayya, , V. Cerundolo

This study shows Sema3A inhibits tumor-specific CD8+ T cell function by inducing cytoskeletal paralysis via NRP1 in the tumor microenvironment.

bioRxiv · Nov 20, 2019Immunology

A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells

E. Abu-Shah, P. Demetriou, S. Balint, V. Mayya, M. A. Kutuzov, O. Dushek, M. L. Dustin

This paper develops a tissue-like platform to study interactions between engineered quiescent human T-cells and dendritic cells, demonstrating CD4 help and PD-1 checkpoint blockade effects.

bioRxiv · Sep 12, 2019Immunology

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T-cells

D. G. Saliba, P. F. Cespedes-Donoso, S. Balint, E. B. Compeer, S. Valvo, K. Korobchevskaya, V. Mayya, Y. Peng, T. Dong, M.-L. Tognoli, E. O Neill, S. Bonham, R. Fischer, B. M. Kessler, M. L. Dustin

The paper identifies synaptic ectosomes released by helper T cells that contain TCR and CD40L, enabling dendritic cell maturation and cytokine production.

bioRxiv · Apr 9, 2019Immunology

CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation.

P. Demetriou, E. Abu-Shah, S. McCuaig, V. Mayya, S. Valvo, K. Korobchevskaya, M. Friedrich, E. Mann, L. Y. Lee, T. Starkey, M. A. Kutuzov, J. Afrose, A. Siokis, Oxford IBD Cohort Investigators, M. Meyer-Hermann, , M. L. Dustin

The paper shows CD2 expression levels determine immunological synapse structure and T-cell activation by influencing CD2-CD58 localization and Src-family kinase recruitment.

bioRxiv · Mar 29, 2019 · PreprintImmunology

Synapse propensity of human memory CD8 T cells confers competitive advantage over naïve counterparts

V. Mayya, E. Judokusumo, E. Abu-Shah, W. Neiswanger, L. C. Kam, M. L. Dustin

The paper shows human memory CD8 T cells have higher synapse propensity than naive cells, giving them competitive advantage in immune responses.

bioRxiv · Dec 28, 2018Immunology

Multifaceted influence of pre-mitotic cytotoxicity of primed CD8 T cells on immunity and infection

D. B. Dandamudi, D. A. Blair, R. Arifa, J. J. Lafaille, M. L. Dustin, V. Mayya

This study investigates how pre-mitotic cytotoxic CD8 T cells (PMCs) influence immune responses and infection outcomes by killing antigen-bearing dendritic cells.

bioRxiv · Nov 2, 2018 · PreprintImmunology