Author

S. McCuaig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Friedrich· 3 shared Oxford IBD Cohort Investigators· 2 shared Z. Christoforidou· 2 shared A. Easton· 1 shared A. Geremia· 1 shared A. Siokis· 1 shared C. V. Arancibia-Carcamo· 1 shared C. Willberg· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

M. Friedrich

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IL-1-driven stromal-neutrophil interaction in deep ulcers defines a pathotype of therapy non-responsive inflammatory bowel disease

M. Friedrich, M. Pohin, M. A. Jackson, I. Korsunsky, S. Bullers, K. Rue-Albrecht, Z. Christoforidou, D. Santhananthan, R. Ravindran, R. Sanches Peres, H. Sharpe, K. Wei, G. F. M. Watts, E. H. Mann, A. Geremia, , F. M. Powrie

bioRxiv · Feb 5, 2021 · PreprintImmunology

TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions

T. Leng, H. Delowar Akther, C.-P. Hackstein, T. King, M. Friedrich, Z. Christoforidou, S. McCuaig, M. Neyazi, C. V. Arancibia-Carcamo, F. Powrie, Oxford IBD Investigators, E. Marchi, R. Sanchesperes, V. Millar, D. Ebner, , P. Klenerman

This study investigates how TCR and inflammatory signals shape human MAIT cell functions, revealing their roles in tissue repair and effector responses.

bioRxiv · May 14, 2019Immunology

CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation.

P. Demetriou, E. Abu-Shah, S. McCuaig, V. Mayya, S. Valvo, K. Korobchevskaya, M. Friedrich, E. Mann, L. Y. Lee, T. Starkey, M. A. Kutuzov, J. Afrose, A. Siokis, Oxford IBD Cohort Investigators, M. Meyer-Hermann, , M. L. Dustin

The paper shows CD2 expression levels determine immunological synapse structure and T-cell activation by influencing CD2-CD58 localization and Src-family kinase recruitment.

bioRxiv · Mar 29, 2019 · PreprintImmunology