Author

T. E. B. Stradal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell signaling & trafficking· 6 Research Focus:cell type annotation· 5 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:imaging· 2

Frequent Co-Authors

K. Rottner· 5 shared A. Steffen· 3 shared S. Stahnke· 3 shared F. Kage· 2 shared J. Faix· 2 shared M. Kirchenwitz· 2 shared M. Müsken· 2 shared M. Schaks· 2 shared

Activity by Year

2020-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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5 shared papersCell Biology

K. Rottner

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Arp2/3 complex-dependent actin regulation protects the survival of tissue-resident mast cells

L. Kaltenbach, M. Mihlan, S. Ulferts, M. Müsken, K. M. Glaser, G. Mittler, M. Babina, M. Innocenti, R. Grosse, T. E. B. Stradal, T. Lämmermann

This study identifies the Arp2/3 complex as critical for maintaining mast cell survival and tissue residency through actin-dependent mechano-protection.

bioRxiv · Feb 23, 2024 · PreprintImmunology

Neurotrophic and immunomodulatory lanostane triterpenoids from wood-inhabiting Basidiomycota

K. Hassan, B. M. Kemkuignou, M. Kirchenwitz, K. Wittstein, M. Rascher, C. Chepkirui, J. C. Matasyoh, C. Decock, R. Koester, T. E. B. Stradal, M. Stadler

This study identifies lanostane triterpenoids from medicinal mushrooms that enhance neurotrophic factors ngf and bdnf without cytotoxicity, suggesting potential for neurodegenerative disease treatment.

bioRxiv · Oct 27, 2022Biochemistry

SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta

M. Kirchenwitz, S. Stahnke, S. Prettin, M. Borowiak, C. Birchmeier, K. Rottner, T. E. B. Stradal, A. Steffen

The paper identifies SMER28 as a compound that inhibits PI3K p110 delta and disrupts receptor tyrosine kinase signaling, leading to autophagy induction and reduced cell growth.

bioRxiv · Dec 10, 2021Cell Biology

Clathrin-independent endocytosis of Human Papillomaviruses is facilitated by actin nucleation promoting factor WASH

P. Brinkert, L. Krebs, P. Samperio Ventayol, L. Greune, C. Bannach, D. Bucher, J. Kollasser, P. Dersch, S. Boulant, T. E. B. Stradal, M. Schelhaas

This study identifies WASH as a facilitator of clathrin-independent endocytosis of HPV16, independent of retromer and SNX-BAR.

bioRxiv · Jun 18, 2021 · PreprintCell Biology

Lamellipodia-like actin networks in cells lacking WAVE Regulatory Complex

F. Kage, H. Doering, M. Mietkowska, M. Schaks, F. Gruener, S. Stahnke, A. Steffen, M. Muesken, T. E. B. Stradal, K. Rottner

The paper shows that lamellipodia-like structures can form without the WAVE Regulatory Complex by using Rac and Cdc42, but not Ena/VASP family proteins.

bioRxiv · Jun 18, 2021 · PreprintCell Biology

Loss of Hem1 disrupts macrophage function and impacts on migration, phagocytosis and integrin-mediated adhesion

S. Stahnke, H. Döring, C. Kusch, D. J. J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, , T. E. B. Stradal

This study shows that Hem1 deficiency impairs macrophage migration, phagocytosis, and integrin-mediated adhesion by disrupting WRC function and paxillin phosphorylation.

Current Biology · May 1, 2021Peer-reviewedCell Biology

Dendritic cell actin dynamics controls T cell priming efficiency at the immunological synapse

A. Leithner, L. M. Altenburger, R. Hauschild, F. Assen, K. Rottner, T. E. B. Stradal, J. V. Stein, M. Sixt

This study shows that dendritic cell actin dynamics, regulated by the WAVE complex, influence T cell priming efficiency at the immunological synapse by modulating synaptic structure and adhesion.

Journal of Cell Biology · Feb 3, 2021Peer-reviewedCell Biology

Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation

G. Dimchev, B. Amiri, A. C. Humphries, M. Schaks, V. Dimchev, T. E. B. Stradal, J. Faix, M. Krause, M. Way, M. Falcke, K. Rottner

This study shows that lamellipodin stabilizes protrusions and promotes adhesion formation, enhancing cell migration efficiency.

Journal of Cell Science · Apr 9, 2020Peer-reviewedCell Biology