Author

P. E. Duffy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

M. Fried· 3 shared J. Y. A. Doritchamou· 2 shared A. A. S. Pinheiro· 1 shared A. Chene· 1 shared A. Dicko· 1 shared A. F. Sander· 1 shared A. J. Spiegel· 1 shared A. Salanti· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

M. Fried

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Author profile →

3 papers

Recent·Most cited

Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

J. Y. A. Doritchamou, M. A. Nielsen, A. Chene, N. K. VIebig, L. E. Lambert, A. F. Sander, J.-P. Semblat, S. Hundt, S. Orr-Gonzalez, C. M. Janitzek, A. J. Spiegel, S. B. Clemmensen, M. L. Thomas, M. C. Nason, M. Snow-Smith, , P. E. Duffy

This study evaluates VAR2CSA-based placental malaria vaccines in Aotus monkeys, finding limited cross-reactivity and functional activity similar to human trials.

bioRxiv · Jun 24, 2022Immunology

A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates

J. Y. A. Doritchamou, J. P. Renn, B. Jenkins, M. Fried, P. E. Duffy

The paper purifies broadly neutralizing antibodies against placental malaria isolates using a single VAR2CSA ectodomain variant and shows it targets epitopes shared by multiple parasites.

bioRxiv · Jul 7, 2021Immunology

CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes

D. S. A. Rodrigues, E. B. Prestes, L. d. S. Silva, A. A. S. Pinheiro, J. M. C. Ribeiro, A. Dicko, P. E. Duffy, M. Fried, I. M. B. Francischetti, E. M. Saraiva, H. A. Paula-Neto, M. T. Bozza

The paper shows that Plasmodium-infected erythrocytes release MIF, which triggers CXCR4-dependent NET formation by neutrophils, contributing to parasite control in malaria.

bioRxiv · Nov 22, 2019Immunology