Author

M. C. Nason

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:non-human primate· 4 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:rat· 1

Frequent Co-Authors

A. Dodson· 3 shared D. R. Flebbe· 3 shared L. Pessaint· 3 shared M. Gagne· 3 shared S. F. Andrew· 3 shared A. Cook· 2 shared A. Van Ry· 2 shared B. J. Flynn· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Dodson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates

M. Gagne, B. J. Flynn, S. F. Andrew, D. R. Flebbe, A. Mychalowych, E. Lamb, M. E. Davis-Gardner, M. R. Burnett, L. A. Serebryannyy, B. C. Lin, L. Pessaint, J.-P. M. Todd, Z. E. Ziff, E. Maule, R. Carroll, , M Suthar

This study shows that mucosal adenoviral-vectored vaccines provide durable protection against XBB.1.16 infection in nonhuman primates, outperforming intramuscular boosting in reducing virus replication in both upper and lower airways.

bioRxiv · Nov 6, 2023 · PreprintImmunology

RBD-based high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways

M. Gagne, B. J. Flynn, C. C. Honeycutt, D. R. Flebbe, S. F. Andrew, S. J. Provost, L. McCormick, A. Van Ry, E. McCarthy, J.-P. M. Todd, S. Bao, I.-T. Teng, S. Marciano, Y. Rudich, C. Li, , D. C. Douek

RBD-62, a high-affinity ACE2 antagonist, limits SARS-CoV-2 replication in both upper and lower airways in rhesus macaques without blocking memory responses or causing anti-drug immunity.

bioRxiv · Jun 9, 2023 · PreprintImmunology

Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

J. Y. A. Doritchamou, M. A. Nielsen, A. Chene, N. K. VIebig, L. E. Lambert, A. F. Sander, J.-P. Semblat, S. Hundt, S. Orr-Gonzalez, C. M. Janitzek, A. J. Spiegel, S. B. Clemmensen, M. L. Thomas, M. C. Nason, M. Snow-Smith, , P. E. Duffy

This study evaluates VAR2CSA-based placental malaria vaccines in Aotus monkeys, finding limited cross-reactivity and functional activity similar to human trials.

bioRxiv · Jun 24, 2022Immunology

Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates

K. S. Corbett, M. C. Nason, B. Flach, M. Gagne, S. O'Connell, T. S. Johnston, S. N. Shah, V. V. Edara, K. Floyd, L. Lai, C. McDanal, J. R. Francica, B. Flynn, K. Wu, A. Choi, , Leung

This study shows that mRNA-1273 vaccine-induced antibody responses correlate with protection against SARS-CoV-2 infection in nonhuman primates.

bioRxiv · Apr 20, 2021 · PreprintImmunology

Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis)

C. L. Finch, I. Crozier, J. H. Lee, R. Byrum, T. K. Cooper, J. Liang, K. Sharer, J. Solomon, P. J. Sayre, G. Kocher, C. Bartos, N. M. Aiosa, M. Castro, P. A. Larson, R. Adams, , J. H. Kuhn

This study uses CT and PET/CT imaging to quantify SARS-CoV-2-induced lung abnormalities in crab-eating macaques, providing an objective endpoint for evaluating medical countermeasures.

bioRxiv · May 14, 2020 · PreprintMicrobiology