Author

P. Fajtov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

A. J. O'Donoghue· 2 shared B. Jagodzinska· 1 shared B. Woodworth· 1 shared C. Yeun· 1 shared D. Skinner· 1 shared I. Meewan· 1 shared J. Campagna· 1 shared J. Kattoula· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. J. O'Donoghue

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2 papers

Recent·Most cited

Identification of a Papain-Like Protease Inhibitor with Potential for Repurposing in Combination with an Mpro Protease Inhibitor for Treatment of SARS-CoV-2

J. Campagna, B. Jagodzinska, P. Alvarez, C. Yeun, P. Spilman, K. M. Enquist, W. Cohn, P. Fajtov, A. J. O'Donoghue, V. Arumugaswami, M. M. H. Li, R. Damoiseaux, V. John

The paper identifies eltrombopag as a PLpro inhibitor that can be repurposed for SARS-CoV-2 treatment, effective in combination with Mpro inhibitors.

bioRxiv · Jul 18, 2022Microbiology

Discovery of Potent Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L

I. Meewan, J. Kattoula, J. Kattoula, D. Skinner, P. Fajtov, M. Giardini, B. Woodworth, J. McKerrow, J. Siqueira-Neto, A. J. O'Donoghue, R. Abagyan

This paper identifies potent triple inhibitors targeting SARS-CoV-2 proteases and human cathepsin L, showing improved potency and antiviral effects compared to disulfiram.

bioRxiv · Oct 19, 2021Pharmacology & Toxicology