Author

P. Spilman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. Soon-Shiong· 3 shared A. Rice· 2 shared A. Shin· 2 shared B. Morimoto· 2 shared E. Gabitzsch· 2 shared H. Adisetiyo· 2 shared J. Balint· 2 shared J. T. Safrit· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

P. Soon-Shiong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of a Papain-Like Protease Inhibitor with Potential for Repurposing in Combination with an Mpro Protease Inhibitor for Treatment of SARS-CoV-2

J. Campagna, B. Jagodzinska, P. Alvarez, C. Yeun, P. Spilman, K. M. Enquist, W. Cohn, P. Fajtov, A. J. O'Donoghue, V. Arumugaswami, M. M. H. Li, R. Damoiseaux, V. John

The paper identifies eltrombopag as a PLpro inhibitor that can be repurposed for SARS-CoV-2 treatment, effective in combination with Mpro inhibitors.

bioRxiv · Jul 18, 2022Microbiology

A deep learning-based iterative digital pathology annotation tool

M. I. Jaber, B. Song, L. Beziaeva, C. W. Szeto, P. Spilman, P. Yang, P. Soon-Shiong

This paper introduces a deep learning-based tool for digital pathology annotation that reduces annotation time while maintaining accuracy, validated on CAMELYON16 and TCGA datasets.

bioRxiv · Aug 23, 2021 · PreprintPathology

Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study

E. Gabitzsch, J. T. Safrit, M. Verma, A. Rice, P. Sieling, L. Zakin, A. Shin, B. Morimoto, H. Adisetiyo, R. Wong, A. Bezawada, K. Dinkins, J. Balint, V. Peykov, H. Garban, , P. Soon-Shiong

hAd5 spike + nucleocapsid SC prime/oral boost vaccine elicits humoral and T-cell responses and protects rhesus macaques from SARS-CoV-2 challenge.

bioRxiv · Dec 8, 2020 · PreprintImmunology

A Next Generation Bivalent Human Ad5 COVID-19 Vaccine Delivering Both Spike and Nucleocapsid Antigens Elicits Th1 Dominant CD4+, CD8+ T-cell and Neutralizing Antibody Responses

A. Rice, M. Verma, A. Shin, L. Zakin, P. Sieling, S. Tanaka, H. Adisetiyo, J. Taft, R. S. Patel, S. Buta, M. Martin-Fernandez, B. Morimoto, E. Gabitzsch, J. T. Safrit, J. Balint, , P. Soon-Shiong

This paper describes a bivalent hAd5 vaccine combining S-Fusion and N-ETSD antigens that elicits strong Th1-biased T-cell and neutralizing antibody responses in pre-clinical models.

bioRxiv · Jul 29, 2020 · PreprintImmunology