Author

W. Cohn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. P. Whitelegge· 3 shared S. S. Hasan· 2 shared A. A. Gholkar· 1 shared A. Christensen· 1 shared A. Haghani· 1 shared A. Hiniker· 1 shared A. J. O'Donoghue· 1 shared B. Doray· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBiochemistry

J. P. Whitelegge

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ApoE isoforms establish distinct antioxidant trajectories across the aging brain

S. J. Shemtov, M. Cacciottolo, A. Christensen, B. Li, A. Haghani, M. C. Rice, H. Anson, C. S. Chung, W. Cohn, H. Zhang, W. J. Mack, A. Hiniker, C. Lee, T. E. Morgan, E. Head, , Max A. Thorwald

This study shows ApoE isoforms influence antioxidant pathways differently across aging, with ApoE4 showing stronger transcriptional responses but less effective protein production, linking to neurodegenerative risk.

bioRxiv · Nov 9, 2026 · PreprintEvolutionary Biology

A single C-terminal residue controls SARS-CoV-2 spike trafficking and virion assembly

D. Dey, E. Qing, Y. He, Y. Chen, B. Jennings, W. Cohn, S. Singh, L. Gakhar, N. J. Schnicker, B. G. Pierce, J. P. Whitelegge, B. Doray, J. P. Orban, T. Gallagher, S. S. Hasan

This study identifies a C-terminal residue critical for SARS-CoV-2 spike protein trafficking and virion assembly, offering insights for vaccine design.

bioRxiv · Mar 9, 2023 · PreprintBiophysics

Identification of a Papain-Like Protease Inhibitor with Potential for Repurposing in Combination with an Mpro Protease Inhibitor for Treatment of SARS-CoV-2

J. Campagna, B. Jagodzinska, P. Alvarez, C. Yeun, P. Spilman, K. M. Enquist, W. Cohn, P. Fajtov, A. J. O'Donoghue, V. Arumugaswami, M. M. H. Li, R. Damoiseaux, V. John

The paper identifies eltrombopag as a PLpro inhibitor that can be repurposed for SARS-CoV-2 treatment, effective in combination with Mpro inhibitors.

bioRxiv · Jul 18, 2022Microbiology

Regulation of Iron Homeostasis Through Parkin-mediated Lactoferrin Ubiquitylation

A. A. Gholkar, S. Schmollinger, E. F. Velasquez, Y.-C. Lo, W. Cohn, J. Capri, H. Dharmarajan, W. J. Deardorff, L. W. Gao, M. Abdusamad, J. P. Whitelegge, J. Z. Torres

This study shows Parkin binds and ubiquitylates lactotransferrin to regulate iron homeostasis, linking Parkin dysfunction to Parkinson's disease.

bioRxiv · Jun 4, 2020Biochemistry

A Novel Chloroplast Super-Complex Consisting of the ATP Synthase and Photosystem I Reaction Center

S. Bhaduri, S. K. Singh, W. Cohn, S. S. Hasan, J. P. Whitelegge, W. A. Cramer

The paper identifies a novel chloroplast super-complex containing ATP synthase and photosystem I in the non-appressed stromal domain of thylakoid membranes.

bioRxiv · Dec 25, 2019Biochemistry