Author

P. Fraczek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

B. D. Cosgrove· 2 shared A. J. De Micheli· 1 shared A. M. Loiben· 1 shared E. H. H. Fong· 1 shared H. Ravichandran· 1 shared I. De Vlaminck· 1 shared J. Chin Cheong· 1 shared K. H. Kim· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

B. D. Cosgrove

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2 papers

Recent·Most cited

Long-term high-yield skeletal muscle stem cell expansion through staged perturbation of cytokine signaling in a soft hydrogel culture platform

A. M. Loiben, K. H. Kim, S. Y. Soueid-Baumgarten, V. M. Aguilar, J. Chin Cheong, R. F. Kopyto, P. Fraczek, E. H. H. Fong, R. Mangal, L. A. Archer, B. D. Cosgrove

This paper develops a method to expand skeletal muscle stem cells long-term using a hydrogel substrate, cytokine cocktail, and staged p38/{beta} inhibition, achieving high yields of functional Pax7+ cells.

bioRxiv · Jun 4, 2020 · PreprintBioengineering

Single-cell analysis of the muscle stem cell hierarchy identifies heterotypic communication signals involved in skeletal muscle regeneration

A. J. De Micheli, P. Fraczek, S. Soueid-Baumgarten, H. Ravichandran, I. De Vlaminck, O. Elemento, B. D. Cosgrove

This study uses scRNA-seq to map muscle stem cell hierarchy and identifies heterotypic communication signals during skeletal muscle regeneration.

bioRxiv · Jun 17, 2019Cell Biology