Author

H. Ravichandran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:cell-cell communication· 4 Approach:experimental assay· 4 Research Focus:differential expression· 3 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

O. Elemento· 5 shared A. F. Rendeiro· 2 shared A. Sboner· 2 shared B. Bhinder· 2 shared J. M. Mosquera· 2 shared J. Manohar· 2 shared A. Amon· 1 shared A. Desmond· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersImmunology

O. Elemento

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry & high-resolution microscopy

E. Hegewisch-Solloa, J. E. Melsen, H. Ravichandran, A. Rendeiro, B. Mundy-Bosse, A. G. Freud, J. C. Melms, S. E. Eisman, B. Izar, E. Grunstein, T. J. Connors, O. Elemento, A. Horowitz, E. M. Mace

This study maps human natural killer cell development in pediatric tonsil using imaging mass cytometry and high-resolution microscopy, revealing stage-specific localization and interactions.

bioRxiv · Sep 5, 2023 · PreprintImmunology

Novel co-culture strategies of tumor organoids with autologous T-cells reveal clinically relevant combinations of immune-checkpoint and targeted therapies

E. Podaza, J. Capuano, M. Al Assaad, H.-h. Kuo, G. Markowitz, A. Irizarry, H. Ravichandran, S. Ackermann, T. Kane, J. Manohar, M. Sigouros, J. Moyer, B. Bhinder, P. Chandra, M. Malbari, , M. L. Martin

The paper develops co-culture strategies of tumor organoids with autologous T-cells to screen immune-checkpoint and targeted therapy combinations.

bioRxiv · Jul 5, 2023 · PreprintImmunology

A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease

S. Rustam, Y. Hu, S. B. Mahjour, S. H. Randell, A. F. Rendeiro, H. Ravichandran, A. Urso, F. d'Ovidio, F. J. Martinez, B. Richmond, V. Polosukhin, J. A. Kropski, T. S. Blackwell, O. Elemento, R. Shaykhiev

This study identifies a unique epithelial cell population in human distal airways and shows its reduction in COPD, linked to IFN-gamma signaling.

bioRxiv · Mar 16, 2022Cell Biology

The evolution of genomic, transcriptomic, and single-cell protein markers of metastatic upper tract urothelial carcinoma

K. Ohara, A. F. Rendeiro, B. Bhinder, K. W. Eng, H. Ravichandran, D. Pisapia, A. Vosoughi, E. Fernandez, K. Shohdy, J. Manohar, S. Beg, D. Wilkes, B. Robinson, F. Khani, R. Bareja, , J. M. Mosquera

The paper examines genomic, transcriptomic, and single-cell protein markers in metastatic upper tract urothelial carcinoma, finding discordant genomic alterations but stable molecular and immune subtypes between primary and metastatic tumors.

bioRxiv · Nov 16, 2021 · PreprintCancer Biology

Aneuploidy and deregulated DNA damage response define haploinsufficiency in breast tissues of BRCA2 mutation carriers

M. Karaayvaz, R. E. Silberman, A. Langenbucher, S. V. Saladi, K. N. Ross, E. Zarcaro, A. Desmond, M. Yildirim, V. Vivekanandan, H. Ravichandran, R. Mylavagnanam, M. C. Specht, S. Ramaswamy, M. Lawrence, A. Amon, L. W. Ellisen

The paper identifies sub-chromosomal copy number variations and DNA damage in BRCA2 mutation carriers' breast tissues, indicating haploinsufficiency and early carcinogenic changes.

bioRxiv · Aug 8, 2019Cancer Biology

Single-cell analysis of the muscle stem cell hierarchy identifies heterotypic communication signals involved in skeletal muscle regeneration

A. J. De Micheli, P. Fraczek, S. Soueid-Baumgarten, H. Ravichandran, I. De Vlaminck, O. Elemento, B. D. Cosgrove

This study uses scRNA-seq to map muscle stem cell hierarchy and identifies heterotypic communication signals during skeletal muscle regeneration.

bioRxiv · Jun 17, 2019Cell Biology