E. H. H. Fong

Eliminating elevated p53 signaling fails to rescue skeletal muscle defects or extend survival in Lamin A/C-deficient mice.

This study investigates whether reducing p53 activation can alleviate skeletal muscle defects in Lamin A/C-deficient mice, but finds no improvement in disease phenotype or survival.

Long-term high-yield skeletal muscle stem cell expansion through staged perturbation of cytokine signaling in a soft hydrogel culture platform

This paper develops a method to expand skeletal muscle stem cells long-term using a hydrogel substrate, cytokine cocktail, and staged p38/{beta} inhibition, achieving high yields of functional Pax7+ cells.