Author

P. G. Sanchez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Das· 1 shared A. H. Wells· 1 shared A. Morris· 1 shared A. Sanchez· 1 shared B. B. Chen· 1 shared B. J. McVerry· 1 shared B. Johnson· 1 shared C. J. Iasella· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Das

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Author profile →

2 papers

Recent·Most cited

CD4+ T cell lymphopenia and dysfunction in severe COVID-19 disease is autocrine TNF-α/TNFRI-dependent

I. Popescu, M. E. Snyder, C. J. Iasella, S. J. Hannan, R. Koshy, R. Burke, A. Das, M. J. Brown, E. J. Lyons, S. C. Lieber, X. Chen, J. C. Sembrat, X. An, K. Linstrum, G. Kitsios, , J. F. McDyer

The paper shows that autocrine TNF-α/TNFRI signaling drives CD4+ T cell lymphopenia and dysfunction in severe COVID-19, and TNF-α blockade improves outcomes.

bioRxiv · Jun 2, 2021 · PreprintImmunology

Top-down engineering of complex communities by directed evolution

C.-Y. Chang, J. C. C. Vila, M. Bender, R. Li, M. C. Mankowski, M. Bassette, J. Borden, S. Golfier, P. G. Sanchez, R. Waymack, X. Zhu, J. Diaz-Colunga, S. Estrela, M. Rebolleda-Gomez, A. Sanchez

This study develops a modeling framework to explore directed evolution strategies for engineering complex microbial communities, identifying effective methods to enhance their stability and functionality.

bioRxiv · Jul 24, 2020Evolutionary Biology