Author

P. Gallant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:Drosophila· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:metagenomics· 1

Frequent Co-Authors

C. Schuelein-Voelk· 2 shared M. Eilers· 2 shared A. Brem· 1 shared A. C. Jacomin· 1 shared A. Kutschke· 1 shared A. Ogunleye· 1 shared A. Orian· 1 shared A. Wiegering· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

C. Schuelein-Voelk

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Direct RNA-binding by MYCN mediates feedback from RNA processing to transcription control

D. Papadopoulos, S. A. Ha, D. Fleischhauer, L. Uhl, K. Schneider, I. Mikicic, T. J. Russell, A. Brem, O. R. Valanju, P. Gallant, C. Schuelein-Voelk, H. M. Maric, P. Beli, G. Buechel, S. M. Vos, M. Eilers

This study shows MYCN binds RNA and regulates transcript turnover, with its RNA-binding activity affecting transcription control through competition with DNA-binding.

bioRxiv · Aug 16, 2023 · PreprintCancer Biology

Spt5 interacts genetically with Myc and is limiting for brain tumor growth in Drosophila

J. Hofstetter, A. Ogunleye, A. Kutschke, L. M. Buchholz, E. Wolf, T. Raabe, P. Gallant

This study shows Spt5 interacts with Myc in Drosophila and is limiting for brain tumor growth, suggesting it as a potential drug target in human oncology.

bioRxiv · Apr 14, 2023 · PreprintCancer Biology

Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling

M. Reissland, O. Hartmann, S. Tauch, C. Prieto-Garcia, C. Schulte, D. Solvie, S. Loebbert, A. C. Jacomin, M. Pesic, J. M. Bugter, C. Schuelein-Voelk, C. Fuss, N. Pahor, C. Ade, V. Buck, , M. E. Diefenbacher

This study identifies USP10 as a deubiquitylase that stabilizes β-Catenin in APC-truncated colorectal cancer, enhancing WNT signaling and cancer stemness.

bioRxiv · Feb 10, 2023 · PreprintCancer Biology