Author

S. M. Vos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Brem· 1 shared C. Schuelein-Voelk· 1 shared D. Fleischhauer· 1 shared D. Papadopoulos· 1 shared E. R. Lee· 1 shared G. Buechel· 1 shared H. M. Maric· 1 shared I. Mikicic· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Brem

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Direct RNA-binding by MYCN mediates feedback from RNA processing to transcription control

D. Papadopoulos, S. A. Ha, D. Fleischhauer, L. Uhl, K. Schneider, I. Mikicic, T. J. Russell, A. Brem, O. R. Valanju, P. Gallant, C. Schuelein-Voelk, H. M. Maric, P. Beli, G. Buechel, S. M. Vos, M. Eilers

This study shows MYCN binds RNA and regulates transcript turnover, with its RNA-binding activity affecting transcription control through competition with DNA-binding.

bioRxiv · Aug 16, 2023 · PreprintCancer Biology

Optimized path planning surpasses human efficiency in cryo-EM imaging

Y. Li, Q. Fan, Z. Xu, E. R. Lee, J. Cohn, V. Demers, J. Y. Lee, L. Yip, M. A. Cianfrocco, S. M. Vos

This paper introduces an algorithm called cryoRL that uses reinforcement learning to optimize cryo-EM data collection, outperforming human operators in efficiency and image quality.

bioRxiv · Jun 17, 2022 · PreprintBiophysics

Structure of transcribing RNA polymerase II-nucleosome complex

L. Farnung, S. M. Vos, P. Cramer

The paper reports the cryo-EM structure of transcribing RNA polymerase II engaged with a nucleosome in yeast, revealing interactions and potential mechanisms for chromatin transcription.

bioRxiv · Oct 16, 2018Biochemistry