Author

P. Guchhait

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

G. Joshi· 2 shared N. M. Shrimali· 2 shared S. Agarwal· 2 shared S. Bhattacharyya· 2 shared S. Kaur· 2 shared T. R. Asuru· 2 shared T. Shrivastava· 2 shared A. Singh· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

G. Joshi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in vitro and in vivo

K. Jakhar, S. Sonar, G. Singh, T. R. Asuru, G. Joshi, N. Beniwal, T. Sarkar, M. Tiwari, J. Kaur, D. K. Rathore, B. Lal, S. Kumar, P. Srivastav, S. Kumar, V. Phagna, , S. Mani

The paper shows that SARS-CoV-2 spike antibodies can enhance DENV2 infection in vitro and in vivo, suggesting potential for increased dengue severity in COVID-19 survivors.

bioRxiv · Oct 9, 2023Immunology

Dietary αKG inhibits SARS CoV-2 infection and rescues inflamed lungs to restore normal O2 saturation in animals

S. Agarwal, S. Kaur, T. R. Asuru, G. Joshi, N. M. Shrimali, A. Singh, O. N. Singh, P. Srivastva, T. Shrivastava, S. Vrati, M. Surjit, P. Guchhait

This study shows dietary αKG inhibits SARS-CoV-2 infection and reduces lung inflammation and thrombosis in animals, restoring oxygen saturation.

bioRxiv · Apr 2, 2022 · PreprintPathology

Alpha-ketoglutarate augments prolyl hydroxylase-2 mediated inactivation of phosphorylated-Akt to inhibit induced-thrombosis and inflammation

N. M. Shrimali, S. Agarwal, S. Kaur, S. Bhattacharya, S. Bhattacharyya, J. T. Prchal, P. Guchhait

This study shows that alpha-ketoglutarate inhibits Akt-driven thrombosis and inflammation by enhancing PHD2 activity and reducing pAkt1 levels in platelets and leukocytes.

bioRxiv · Jun 11, 2021Pathology