Author

P. J. Brennan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. Agrawal· 1 shared A. B. Benowitz· 1 shared A. Goodridge· 1 shared A. Konopacka· 1 shared A. R. Mola· 1 shared A. Saudemont· 1 shared A. Traslavina Lopez· 1 shared C. M. Deane· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. Agrawal

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Author profile →

3 papers

Recent·Most cited

Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells

P. J. Brennan, R. E. Saunders, M. Spanou, M. Serafini, L. Sun, G. P. Heger, A. Konopacka, R. D. Beveridge, L. Gordon, S. B. Bunally, A. Saudemont, A. B. Benowitz, C. Martinez-Fleites, M. A. Queisser, H. An, , S. J. Conway

The paper designs a selective protein degradation system using bumped IMiD analogs and zinc-finger degrons to target specific proteins without affecting endogenous substrates.

bioRxiv · Mar 15, 2024Biochemistry

Cell walls are dynamically O-acetylated in the green seaweed, Ulva compressa

J. H. Bothwell, A. Goodridge, M. Rapin, P. J. Brennan, A. Traslavina Lopez, A. Agrawal, S. C. Fry, G. Campbell, J. Blomme

The paper identifies O-acetylation in Ulva compressa cell wall polymers, showing dynamic changes under stress and potential gene involvement.

bioRxiv · May 24, 2022 · PreprintCell Biology

A genome-wide innateness gradient defines the functional state of human innate T cells

M. Gutierrez-Arcelus, N. Teslovich, A. R. Mola, H. Kim, S. Hannes, K. Slowikowski, G. F. M. Watts, M. Brenner, S. Raychaudhuri, P. J. Brennan

The paper identifies an innateness gradient in human T cells, showing a trade-off between effector function and proliferative capacity.

bioRxiv · Mar 13, 2018Immunology